Blockade of Mineralocorticoid and Glucocorticoid Receptors Reverses Stress-Induced Motor Impairments

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Blockade of mineralocorticoid and glucocorticoid receptors reverses stress-induced motor impairments.

AIM Stress and glucocorticoids can influence movement performance and pathologies of the motor system. The classic notion assumes that the glucocorticoid receptor (GR) mediates the majority of stress-induced behavioral changes. Nevertheless, recent findings have attributed a more prominent role to the mineralocorticoid receptor (MR) in modulating behavior. The purpose of this study was to disso...

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ژورنال

عنوان ژورنال: Neuroendocrinology

سال: 2011

ISSN: 1423-0194,0028-3835

DOI: 10.1159/000329988